Mo’men Shabib, Ameen Mahmoud, Mohammad Al-Sharab, Ahmed Al-Karasneh and Osama Al-Ramahi
Background: Diabetic macular edema can significantly hinder the life of many diabetic patients. Research has shown that intravitreal injections and laser effectively target this serious complication. This study aims to compare the effectiveness and safety of Ranibizumab and Triamcinolone when combined with prompt laser in treating diabetic macular edema.
Methods: We systematically gathered research papers from the major databases ncluding PubMed, cochrane, Scopus, Elsevier, EBSCO, Sage. Following the appropriate guidelines tailored towards contrasting the effectiveness an safety between Ranibizumab and Triamcinolone in patients with diabetic macular edema.
Results: This meta-analysis found that Ranibizumab is more effective in targeting diabetic macular edema in terms of OCT readings and retinal structures, whereas Triamcinolone was associated better disease control and less systemic side effects.
Conclusion: These results demonstrate the need for a patient-centered treatment plan that takes into account the efficacy and safety of each drug combined with the individual risk factors of each patient with diabetic macular edema.
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